Join us as our Senior Director or Vice President Clinical, Oncology

Thryv Therapeutics Inc. is a privately owned company based in Montreal, Quebec, Canada. We have been pioneering a precision medicine approach to treat Long QT Syndrome via SGK1 inhibition since 2019 and have since evolved our portfolio to include the treatment of resistant and rare cancers.

OPPORTUNITY SUMMARY

The Senior Director or Vice President Clinical, Oncology will report to the Chief Medical Officer and will be responsible for overseeing the strategic and clinical development of the Thryv Therapeutics’ Oncology Program in collaboration with Clinical Operations, Regulatory, and Translational Research.

KEY RESPONSIBILITIES

  • Lead clinical and strategic efforts in oncology to establish safety, PK/PD, and dose justification, to establish proof of concepts, and ultimately clinical development strategy to secure regulatory approvals.

  • Work with teams to identify best options, evaluate indications and designs and propose scenarios and recommendations to seek Executive Committee and Board of Directors approval.

  • Develop and review FDA documents (e.g., briefing documents, IND, NDA) and study related documents (e.g., Investigator Brochure, CRFs, protocol, CSRs, etc.)

  • Provide clinical regulatory science research expertise, especially regarding study design, data interpretation, and Safety Review Committee input.

  • Direct staff to ensure efficiency for day-to-day operations and to meet the goals of the program.

  • Contribute to the cross-functional development team from the clinical and scientific perspective to achieve corporate goals.

EDUCATION & WORK EXPERIENCE

  • MD or MD/PhD degree with 6+ years experience in clinical oncology drug development; experience in immuno-oncology is an advantage.

TECHNICAL KNOWLEDGE & SKILLS

  • Demonstrated clinical research experience in early stage and late-stage development including first-in human trials, proof of concept trials and registration-directed trials; experience with implementation and analysis of pharmacodynamic and potential predictive biomarkers in clinical trials is an advantage.

  • Experience with strategic alliances and/or collaborations.

  • Proven ability to provide solutions to a variety of technical problems of moderate scope and difficult complexity.

  • Excellent written and verbal communication skills, including ability to effectively present information and respond to questions from project teams, external vendors, investors, investigators, and KOLs.

NON-TECHNICAL SKILLS & COMPETENCIES

  • Exudes the highest level of integrity and an acute sense of ethics.

  • Operates with a sense of urgency and perseverance to achieve results.

  • Superior problem solving, conflict management and interpersonal skills.

  • Ability and enthusiasm to work in a cross-functional team environment.

  • Superior organizational skills and the ability to multi-task and prioritize competing assignments.

  • Excellent oral/written communication, interpersonal, organizational and presentation skills.

  • Proactive and self-motivated with the ability to work independently with minimal supervision.

  • Ability to work under pressure to meet deadlines.

  • Strong leadership qualities.

  • Ability to travel up to 20% of the time.

EQUAL OPPORTUNITY WORKPLACE

Thryv Therapeutics Inc. is proud to be an equal opportunity workplace. We are committed to equal employment opportunity regardless of race, colour, religion, sex, sexual orientation, gender identity, age, national origin, disability, and any other characteristic protected by law.

APPLY

Please send your resume and cover letter to admin@thryvtrx.com